Medical Oncology

Medical Oncology

State-of-the-Art Systemic Cancer Therapy - Personalized for Every Patient.

Targeted therapies, immunotherapy, and precision chemotherapy delivered by disease-focused experts.

The Medical Oncology department provides comprehensive systemic cancer therapy, including cytotoxic chemotherapy, hormone therapy, small-molecule targeted agents, antibody-drug conjugates, bispecifics, checkpoint inhibitors, CAR-T referral coordination, and supportive care medications. Weekly multidisciplinary tumor boards ensure that each patient receives evidence-based, patient-centered treatment, integrating pathology, radiology, surgery, radiation oncology, genetics, and palliative care.

42

fellowship-trained medical oncologists across 6 disease-site teams

25,000+

systemic therapy infusions and 4,200 oral targeted therapy starts in 2024

90%

molecular profiling rate for solid tumors at diagnosis

250+

active clinical trial slots (Phase I–III) with 38% patient participation

Common Conditions & Subspecialty Clinics.

  • Management of immune-related adverse events 
  • Pharmacogenomics-guided therapy 
  • Tumor-agnostic treatments (NTRK, MSI-H, TMB-high) 

  • Glioblastoma and low-grade gliomas 
  • Brain metastases management
  • Temozolomide (TMZ), Tumor Treating Fields (TTFields) 
  • Vaccine and immunotherapy clinical trials 

  • Cutaneous and mucosal melanoma 
  • Merkel cell carcinoma 
  • PD-1 and LAG-3 checkpoint inhibitor combinations 
  • BRAF/MEK inhibitors, intralesional therapies 

  • Bone and soft-tissue sarcomas 
  • Gastrointestinal stromal tumors (GIST), desmoid tumors 
  • Tyrosine kinase inhibitors (TKIs) 
  • Integration with CyberKnife/SBRT for local control 

  • Prostate, bladder, kidney, and testicular cancers 
  • Androgen-receptor pathway inhibitors 
  • Immunotherapy and VEGF combination regimens 
  • Coordination for PSMA-targeted therapies 

  • Non-small cell lung cancer (NSCLC) — driver-positive & wild-type 
  • Small-cell lung cancer (SCLC) and mesothelioma 
  • Targeted therapy for EGFR, ALK, ROS1, MET mutations 
  • Immunotherapy and TKI resistance clinical trials 

  • HR-positive/HER2-negative breast cancer 
  • HER2-positive and triple-negative breast cancer 
  • Neoadjuvant chemotherapy and endocrine therapy 
  • Maintenance therapy with CDK4/6 and PARP inhibitors 

Procedures & Treatments.

Early palliative-care co-management for symptom relief and QoL

Integration with cardio-oncology for LV function monitoring

Onco-fertility counseling and cryopreservation prior to gonadotoxic therapy

Anti-emetics per MASCC/ESMO guidelines, oral cryotherapy for mucositis

Growth-factor support (G-CSF), erythropoiesis-stimulating agents

Intrathecal Chemotherapy

For CNS prophylaxis/treatment in leukemia & lymphoma

Bisphosphonates & RANK-Ligand Inhibitors

Skeletal-related-event prevention

Hormone Therapy

SERMs, SERDs, aromatase inhibitors, androgen-receptor antagonists

Antibody-Drug Conjugates (ADC)

T-DM1, trastuzumab-deruxtecan, sacituzumab, enfortumab

Immunotherapy

PD-1/PD-L1, CTLA-4, LAG-3 inhibitors; bispecific T-cell engagers

Targeted Therapy

TKIs (EGFR, ALK, ROS1, RET, FGFR, BRAF, MEK), PARP inhibitors, CDK4/6 inhibitors, PI3K/mTOR inhibitors

Cytotoxic Chemotherapy

Dose-dense, metronomic, and hyperfractionated regimens

Liquid-biopsy MRD surveillance studies

Real-world evidence registry for TKI resistance and sequencing

First-in-human immunotherapy combinations (anti-TIM-3, TIGIT)

Phase I basket & umbrella trials targeting rare mutations

Care Pathway & Coordination.

1
Rapid Molecular Profiling

Rapid Molecular Profiling

NGS and IHC results within 5–7 days of biopsy.

2


Tumor Board Consensus

Tumor Board Consensus

Disease-site board formulates treatment algorithm and trial eligibility.

3


Treatment Education & Consent

Treatment Education & Consent

Oncology nurse and pharmacist review regimen, side effects, and supportive medications.

4


Therapy Administration

Therapy Administration

Infusion in USP 800-compliant suite or oral targeted therapy with adherence app.

5


Monitoring & Response Assessment

Monitoring & Response Assessment

Labs every cycle, imaging per RECIST 1.1, ctDNA tracking.

6


Survivorship / Next-Line Planning

Survivorship / Next-Line Planning

Transition to survivorship clinic or next-line therapy; trial screening each line.

Technology & Facilities.

USP 800 Cleanroom Oncology Pharmacy

Robotic compounding and barcode verification

AI Symptom-Monitoring App

Patient-reported outcomes trigger nurse calls, reducing ED visits by 25%

Automated Infusion Pumps with Gravimetric Verification

On-Site NGS & ctDNA Lab

500-gene panel with 7-day TAT

Infusion Center

48 private bays with HEPA filtration, reclining chairs, and entertainment

Virtual Trial-Matching Platform

Real-time eligibility screening across global databases

Our Experts.

Dr. Dima Abdul Jabbar

Dr. Dima Abdul Jabbar

Consultant Medical Oncology and Director of Burjeel Breast Center
Prof. Dr.Marwane Ghosn

Prof. Dr.Marwane Ghosn

Consultant Medical Oncology
Dr. Haitham Al-Okk

Dr. Haitham Al-Okk

Consultant Medical Oncology
Dr. Hassan Jaafar

Dr. Hassan Jaafar

Consultant Medical Oncology
Prof. Humaid Obaid Bin Harmal Al Shamsi

Prof. Humaid Obaid Bin Harmal Al Shamsi

Consultant & Director of Oncology
Dr. Sonia Otsmane

Dr. Sonia Otsmane

Consultant Medical Oncology
Dr. Amin M. Abyad

Dr. Amin M. Abyad

Specialist Medical Oncology & Internal Medicine
Dr. Mawada Hussein

Dr. Mawada Hussein

Specialist Medical Oncology
Dr. Nadia Abdelwahed

Dr. Nadia Abdelwahed

Specialist Medical Oncologist
Dr. Tariq Alhamid

Dr. Tariq Alhamid

Medical Oncology Specialist
Dr. Wessam Alkrad

Dr. Wessam Alkrad

General Practitioner

Patient Stories.

Click Here
A Healing Journey At Burjeel Cancer Institute

A Healing Journey At Burjeel Cancer Institute

Bassam

Multiple Myeloma

Frequently Asked Questions.

Will I lose my hair?

Only certain chemotherapies cause hair loss. Many targeted and immunotherapies do not. Scalp-cooling caps are available.

Are clinical trials safe?

Yes, all trials are overseen by ethics committees. Safety is continuously monitored, and many provide access to breakthrough therapies.

Can I take treatment at home?

Yes, oral targeted therapies and home subcutaneous injections are possible. We provide adherence support and tele-oncology check-ins.

How are side effects managed?

We proactively manage side effects with anti-emetics, growth factors, and early palliative-care support. A side-effect hot-line is available 24/7.

Ready to Start Your Health Journey?

Take the first step towards better health with our expert team.

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